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Restem (Zolpidem)

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Restem is a sedative, also called a hypnotic. Restem affects chemicals in the brain that may be unbalanced in people with sleep problems insomnia). Restem is used to treat insomnia. The immediate-release tablet is used to help you fall asleep when you first go to bed. The extended-release form, Ambien CR, which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep.

Other names for this medication:
Ambiz, Ambulax, Azold, Dactive, Getrest, Insom, Inzofresh, Isodem, Kayzole, Lipidem, Lopitas, Lypin, Nidra, Nitrest, Olpid, Restem, Sobrium, Stilnoct, Syzol, Zanlop, Zedem, Zleep, Zodem, Zolax, Zolcent, Zoldem, Zolep, Zolfresh, Zolip, Zolit, Zolnex, Zolojet, Zolpel, Zolpiapt, Zolpid, Zolpidem, Zolpimist, Zolpirest, Zolpistar, Zolpitrac, Zolsoma, Zoltar, Zolway, Zomnia, Zopid

Similar Products:
Thorazine, Cytoxan, Cymbalta, Exelon, Benicar, Vantin, Zyloprim, Claritin, Luvox, Glinate, Theofil, Spaclovir, Norflohexal, Atelol, Ziglim, Atanaal,

Also known as: Zolpidem


Restem (zolpidem tartrate) is a gamma-aminobutyric acid (GABA) A agonist of the imidazopyridine class and is available in 5 mg and 10 mg strength tablets for oral administration.

Zolpidem tartrate is a white to off-white crystalline powder that is sparingly soluble in water, alcohol, and propylene glycol. It has a molecular weight of 764.88.

Each Restem tablet includes the following inactive ingredients: hydroxypropyl methylcellulose, lactose, magnesium stearate, micro-crystalline cellulose, polyethylene glycol, sodium starch glycolate, and titanium dioxide. The 5 mg tablet also contains FD&C Red No. 40, iron oxide colorant, and polysorbate 80.


Restem sublingual tablets (Edluar) are available in strengths of 5 mg and 10 mg. Place the sublingual tablet under the tongue, where it will disintegrate. Do not swallow the tablet or take it with water. Restem oral spray (Zolpimist) is available as a cherry-flavored spray solution in a container. Each spray delivers 5 mg of Restem.

Restem rapid-acting sublingual tablets (Intermezzo) are available in strengths of 1.75 mg and 3.5 mg. Take the rapid-acting sublingual tablet in bed when you wake up in the middle of the night and have difficulty going back asleep. While in bed, place the tablet under your tongue and allow it to break apart completely. Do not swallow it whole.


An overdose of Restem can be fatal.

Symptoms of an Restem overdose include extreme drowsiness, weakening of heart and breathing function, and coma.

If you think you have taken too much Restem, or someone else has taken too much, seek emergency medical attention immediately to get appropriate treatment.


Store Restem at room temperature away from moisture, heat, and light.

Store the liquid form of Restem in the refrigerator.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Side effects

The most common side effects associated with Restem are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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